Dad’s Contribution

Older fathers may have children with higher risk of psychiatric disorders, according to a study.

Written byAbby Olena, PhD
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Human spermatozoaWIKIMEDIA, FORSKERUNVWhile most people are familiar with the complications that can occur in children of older mothers, evidence is increasing for the impact of the father’s age on the health of the child. A team of researchers from Indiana University and the Karolinska Institute in Sweden has shown that children of older fathers may have increased risk of some psychiatric disorders. Their work was published in JAMA Psychiatry this week (February 26).

“Paternal age may have a stronger effect than we previously realized,” coauthor Brian D’Onofrio of Indiana University told NPR.

The investigators used data available for more than 2.5 million individuals born between 1973 and 2001 in Sweden from more than 1.4 million distinct fathers. They found that, compared to fathers from 20 to 24 years old, children born to fathers 45 and older had a higher risk of autism spectrum disorders, attention-deficit/hyperactivity disorder, bipolar disorder, substance abuse, suicide attempts, and psychosis. The researchers also found that children born by fathers of advanced age were more likely to have failed a grade and have lower overall educational achievement.

“The older age of dads is associated with not just one disorder or another, but with a large ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

    View Full Profile
Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

The Scientist Placeholder Image

Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

OGT logo

OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel