Diane Pennica

Being a woman helped Diane Pennica to make the greatest breakthrough of her career, but not in a way one might expect.

Written byAnne Harding
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Courtesy of Diane Pennica

Being a woman helped Diane Pennica to make the greatest breakthrough of her career, but not in a way one might expect.

In 1980, just a month after being hired at Genentech, Pennica found herself at a meeting on fibrinolysis in Sweden, where 30 scientists, all men, were listening to Desire Collen describe how he'd used protein purified from melanoma cells to dissolve a blood clot in a patient's leg.

The protein was tissue plasminogen activator (TPA), and Genentech had sent Pennica to the meeting for the express purpose of finding a substance that could be used to dissolve clots in patients who had had heart attacks. "This was exactly what Genentech had sent me to hear," she recalls.

But she wasn't supposed to be in that room. By accident, she'd slipped into a private preconference session. "They didn't ask me to leave right away because ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Meet the Author

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH