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DNA Hard Drive

Researchers design the first rewritable biological data storage system.

Written byMegan Scudellari
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NATIONAL HUMAN GENOME RESEARCH INSTITUTE

Researchers at Stanford University in California have programmed DNA to function as a rewritable biological data storage system. The research was published Monday (May 21) in the Proceedings of the National Academy of Sciences.

"One of the coolest places for computing is within biological systems," senior author Drew Endy told the BBC. His team spent three years designing the system, which consists of two enzymes that splice DNA sequences from a bacteriophage—a bacteria-infecting virus—into the E. coli genome. Once inserted, the DNA sequence points in one of two directions, like a '0' or a '1' in binary. Based on its orientation, the inserted gene expresss either a green or red fluorescent protein, causing the cell to glow green or red.

Past DNA-based storage systems, which ...

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