First US Penis Transplant

A man who lost his penis due to cancer has received the organ from a deceased donor.

Written byTanya Lewis
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

WIKIMEDIA, RUHRFISCHThomas Manning, 64, of Halifax, Massachusetts, is the first person in the United States to receive a penis transplant, The New York Times (NYT) reported today (May 16). During a 15-hour operation on May 8 and 9, a surgical team led by Curtis Cetrulo Jr. and Dicken Ko of Massachusetts General Hospital (MGH) in Boston successfully grafted an organ from a deceased donor onto the patient, who had his penis removed three years ago because of a rare form of cancer.

“We’re very cautiously optimistic,” Cetrulo, a plastic and reconstructive surgeon at MGH, said in a briefing today. If everything goes according to plan, Manning should be able to urinate normally within a few weeks and could recover sexual function in weeks to months, Cetrulo told NYT.

The experimental procedure, known as a genitourinary vascularized composite allograft (GUVCA), was the result of more than three years of research and planning, according to an MGH statement. To prevent rejection of the organ, Manning will likely have to take immune-suppressant drugs for the rest of his life. These medications can have serious side effects, such as an increased risk of cancer or kidney damage, but the patient is aware of these risks, Ko said in the briefing.

Ultimately, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies