Five Things Not to Forget When Forecasting

Forecast models can become complex, but the principles for gathering and vetting data for good predictions should remain basic.

Written byKen Wilan
| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

In 1997, Centocor had a promising drug in Phase II trials and a pharmaceutical company, Schering-Plough, interested in a deal to market it internationally. The only problem was that the drug, a biologic aimed at Crohn disease and rheumatoid arthritis, would be first in the space and thus no historical data existed about the size of the potential market. That number, of course, was key to the company's future.

"The historical research wasn't very useful, so we needed new information," says James Schoeneck, then general manager of the immunology business unit at Centocor and a key negotiator in the deal. Enter forecasting. Centocor did its information gathering and modeling, and entered negotiations projecting an approximate $1 billion international market by 2007. Schering-Plough, however, predicted annual sales of around $300 million.

While the two companies were far apart in their forecasts, Schoeneck's team was confident that it had done a thorough ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies