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The retina can adjust to a remarkably wide range of illumination; from starlight to sunlight, natural light intensity varies more than 11 orders of magnitude. Rods and cones, the cells that translate light signals into a neural response, use multiple molecular mechanisms to prevent them from becoming blinded as light intensities increase throughout the day.

Recent work on rats from Vadim Arshavsky, associate professor of ophthalmology, Harvard University, and his colleagues have revealed...

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