Fueling the Fires of RNA Interference

World RNAi Market 2010Contract service = outsourced research/target validation projects Total = Projected worldwide RNAi revenues for 2010, in US dollars Source: Frost & SullivanScientists hunger for breakthroughs in the lab, but it's the venture capitalists who continually scout the life sciences for the next great money-making bonanza. After a pivotal study in the May 2001 issue of Nature showed that RNA could effectively silence gene expression in mammalian cell lines, RNA interference (R

Written byKaren Pallarito
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Contract service = outsourced research/target validation projects Total = Projected worldwide RNAi revenues for 2010, in US dollars Source: Frost & Sullivan

Scientists hunger for breakthroughs in the lab, but it's the venture capitalists who continually scout the life sciences for the next great money-making bonanza. After a pivotal study in the May 2001 issue of Nature showed that RNA could effectively silence gene expression in mammalian cell lines, RNA interference (RNAi) began to look like a possible contender.

Right out of the box, RNAi proved be an extremely useful tool for validating potential drug targets in the laboratory. A quick and easy way to see what happens to cells when a gene is knocked out, RNAi can potentially speed up the process of designing molecules to block unwanted messages. It also takes a fraction of the cost and time of creating a single knockout mouse. "As a research tool ...

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