GM Mosquito Cuts Wild-Type Numbers

Release of a transgenic version of Aedes aegypti, a species that can carry dengue virus, decimated a local population of non-mutated mosquitoes, according to a study.

Written byKerry Grens
| 2 min read

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FREESTOCKPHOTOS.BIZ, CDC/PROF FRANK HADLEY COLLINSA genetically modified (GM) mosquito—designed to infiltrate a wild population and produce offspring that die before reproductive age—has devastated local mosquito numbers in a field trial in Brazil. Researchers reported in PLOS Neglected Tropical Diseases this month (July 2) that one year after deployment of the mutant Aedes aegypti, mosquito numbers were reduced 80 percent to 95 percent.

“The fact that the number of Aedes aegypti adults were reduced by 95% in the treatment area confirms that the Oxitec mosquito does what it is supposed to and that is to get rid of mosquitoes,” study coauthor Andrew McKemey, head of field operations at Oxitec, which developed the GM mosquito, said in a press release.

Aedes aegypti can carry pathogens that cause diseases, including dengue and chikungunya. Although McKemey’s study did not determine whether disease burden among humans would drop with the introduction of GM mosquitoes, he said in the statement that “according to published mathematical models reviewed and recommended by the World Health Organization (WHO) working group on dengue, it would . . . reduce the number of biting mosquitoes below the disease ...

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  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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