Horizon Discovery Group plc (LSE:HZD) (Horizon), a leading provider of research tools to support translational genomics and the development of personalized medicines, today announced the launch of gUIDEbook™, developed in collaboration with Desktop Genetics. gUIDEbook bioinformatics software has been designed to support researchers working with CRISPR genome editing.
The software is free of charge to use and can be accessed via the Horizon website: https://www.horizondiscovery.com/what-we-do/discovery-toolbox/genassist-crispr--raav-genome-editing-tools
Successful CRISPR genome editing relies on the quality of the gRNA design, determined by bioinformatic software. The gUIDEbook software has been developed to provide the most complete solution available for designing CRISPR genome editing experiments. The platform enables researchers to generate knock-outs, knock-ins, mutations or tags through powerful laboratory-validated DNA search algorithms behind a simple and intuitive user interface.
Utilizing state-of-the-art scoring functions, gUIDEbook allows an entire gene to be quickly reviewed for the best guide or guides for both wild-type and Cas9 ‘nickase’ experiments. ...
