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Helper Plasmids Lend a Hand to AAV Production

An innovative helper plasmid improves adeno-associated virus quality and infectivity.

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Safe and effective gene therapy strategies depend on robust and reliable adeno-associated virus (AAV) mediated therapeutic gene delivery. However, scaling up AAV manufacturing to obtain sufficient yields to meet the demands of new research initiatives and clinical applications is challenging using traditional approaches.

Download this article from Polyplus, now part of Sartorius, to learn how new technology enables AAV production with better yields, quality, and infectivity.

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3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.
February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

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