Helpers and Killers

For this article, Ricki Lewis interviewed Polly Matzinger, section head for T-cell tolerance and memory at the National Institute of Allergy and Infectious Diseases, William Heath, senior research fellow in the immunology division of the Walter and Eliza Hall Institute of Medical Research in Melbourne, and Stephen P. Schoenberger, assistant member in the division of immune regulation at the La Jolla Institute for Allergy and Immunology. Data from the Web of Science (ISI, Philadelphia) show that these papers have been cited 50 to 100 times more often than the average paper of the same type and age. J.P. Ridge, F. Di Rosa, and P. Matzinger, "A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell," Nature, 393:474-8, 1998. (Cited in more than 250 papers since publication) S.R.M. Bennett, F.R. Carbone, F. Karamalis, R.A. Flavell, J.F.A.P. Miller, and W.R. Heath, "Help for cytotoxic-T-cell responses ...