Human Mesenchymal Stem Cells Differentiate in the Lab

While prominent scientists plead with legislators to reconsider their conservative stance on funding human embryonic stem (ES) cell research, a six-year-old company in Baltimore is quietly making the matter moot. In a just-released tour-de-force research report, it is no longer quite so quiet.1 Researchers at Osiris Therapeutics and the Johns Hopkins University School of Medicine coaxed human mesenchymal stem cells (hMSCs) from adults' bone marrow to develop into cartilage, fat, and bone cells

| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

While prominent scientists plead with legislators to reconsider their conservative stance on funding human embryonic stem (ES) cell research, a six-year-old company in Baltimore is quietly making the matter moot. In a just-released tour-de-force research report, it is no longer quite so quiet.1

Researchers at Osiris Therapeutics and the Johns Hopkins University School of Medicine coaxed human mesenchymal stem cells (hMSCs) from adults' bone marrow to develop into cartilage, fat, and bone cells, in vitro. With many millions of people suffering from cartilage injury, poorly healing fractures, heart disease, cancer, and the degenerative conditions of aging, the potential market for stem cell-based regenerative medicine is gargantuan. And the fact that the cells come from adults may neatly bury objections to using cells from embryos.2 "It won't be necessary to use ES cells if we can do therapy with adult-derived stem cells. Nor are we creating organisms, but supplying stem cells ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Ricki Lewis

    This person does not yet have a bio.

Published In

Share
Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue
Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

Element Bioscience Logo
Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
The Scientist Placeholder Image

Seeing and Sorting with Confidence

BD
The Scientist Placeholder Image

Streamlining Microbial Quality Control Testing

MicroQuant™ by ATCC logo

Products

The Scientist Placeholder Image

Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

parse-biosciences-logo

Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

waters-logo

How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis