Human Mesenchymal Stem Cells Differentiate in the Lab

While prominent scientists plead with legislators to reconsider their conservative stance on funding human embryonic stem (ES) cell research, a six-year-old company in Baltimore is quietly making the matter moot. In a just-released tour-de-force research report, it is no longer quite so quiet.1 Researchers at Osiris Therapeutics and the Johns Hopkins University School of Medicine coaxed human mesenchymal stem cells (hMSCs) from adults' bone marrow to develop into cartilage, fat, and bone cells

| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

While prominent scientists plead with legislators to reconsider their conservative stance on funding human embryonic stem (ES) cell research, a six-year-old company in Baltimore is quietly making the matter moot. In a just-released tour-de-force research report, it is no longer quite so quiet.1

Researchers at Osiris Therapeutics and the Johns Hopkins University School of Medicine coaxed human mesenchymal stem cells (hMSCs) from adults' bone marrow to develop into cartilage, fat, and bone cells, in vitro. With many millions of people suffering from cartilage injury, poorly healing fractures, heart disease, cancer, and the degenerative conditions of aging, the potential market for stem cell-based regenerative medicine is gargantuan. And the fact that the cells come from adults may neatly bury objections to using cells from embryos.2 "It won't be necessary to use ES cells if we can do therapy with adult-derived stem cells. Nor are we creating organisms, but supplying stem cells ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Ricki Lewis

    This person does not yet have a bio.

Published In

Share
TS Digest January 2025
January 2025, Issue 1

Why Do Some People Get Drunk Faster Than Others?

Genetics and tolerance shake up how alcohol affects each person, creating a unique cocktail of experiences.

View this Issue
Sex Differences in Neurological Research

Sex Differences in Neurological Research

bit.bio logo
New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Sino
New Approaches for Decoding Cancer at the Single-Cell Level

New Approaches for Decoding Cancer at the Single-Cell Level

Biotium logo
Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

Acro 

Products

Conceptual 3D image of DNA on a blue background.

Understanding the Nuts and Bolts of qPCR Assay Controls 

Bio-Rad
Takara Bio

Takara Bio USA Holdings, Inc. announces the acquisition of Curio Bioscience, adding spatial biology to its broad portfolio of single-cell omics solutions

Sapio Sciences

Sapio Sciences Announces Enhanced Capabilities for Chemistry, Immunogenicity, GMP and Molecular Biology

Biotium Logo

Biotium Unveils the Most Sensitive Stains for DNA or RNA with New EMBER™ Ultra Agarose Gel Kits