Humans Meet Neanderthals: The Prequel

The earliest interbreeding between humans and Neanderthals took place at least 100,000 years ago—millennia earlier than previously thought.

Written byCatherine Offord
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Interbreeding around 60,000 years ago (green arrow) accounts for Neanderthal DNA in modern humans; human DNA in the Neanderthal genome likely came about due to earlier interbreeding (red arrow).© ILAN GRONAU

Neanderthals diverged from modern humans at least 430,000 years ago. Research in the last decade has estimated that the two hominid groups interbred multiple times in the last 60,000 years, during encounters in the Middle East and, later, in Eastern Europe. But a study published in Nature on Wednesday (February 17) has provided evidence that humans also interbred with Neanderthals 40 millennia previously.

“An early modern human population left Africa much earlier than had been shown before,” study coauthor Sergi Castellano of Germany’s Max Planck Institute for Evolutionary Anthropology told The Guardian. These humans “met with Neanderthals, possibly those moving from Europe towards the East, some time around 100,000 years ago.”

To produce this estimate, the researchers reanalyzed the genome of a female Neanderthal who ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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