For this article, Jennifer Fisher Wilson interviewed Emmanuel Mignot, Center for Narcolepsy, department of psychiatry, Stanford University School of Medicine, in Stanford, Calif., and Masashi Yanagisawa, Howard Hughes Medical Institute investigator, department of molecular genetics, University of Texas Southwestern Medical Center at Dallas. Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age.

L. Lin, J. Faraco, R. Li, H. Kadotani, W. Rogers, X.Y. Lin, X.H. Qiu, P.J. de Jong, S. Nishino, E. Mignot, "The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene," Cell, 98[3]:365-76 Aug. 6, 1999. (Cited in 179 papers)

R.M. Chemelli, J.T. Willie, C.M. Sinton, J.K. Elmquist, T. Scammell, C. Lee, J.A. Richardson, S.C. Williams, Y.M. Xiong, Y. Kisanuki, T.E. Fitch, M. Nakazato, R.E. Hammer, C.B. Saper,...

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