Infographic: Capturing a More Complete Picture of Expression

CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.

Deanna MacNeil, PhD headshot
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Scientists mix single cells with ADTs and encapsulate them in droplets, along with microbeads. Cell lysis within the droplet releases mRNAs and antibody-derived tags (ADT) for microbead capture before PCR amplification, size separation, and single cell RNA sequencing (scRNA-seq).

Infographic showing how CITE-seq detects protein and gene expression in the same cell
© MESA SCHUMACHER

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Meet the Author

  • Deanna MacNeil, PhD headshot

    Deanna MacNeil, PhD

    Deanna earned their PhD in cellular biology from McGill University in 2020 and has a professional background in medical writing. They are an associate science editor at The Scientist.

Published In

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