CITE-seq draws upon the unbiased nature of single-cell RNA sequencing to gather new insights about protein and gene expression within the same cell.
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Scientists mix single cells with ADTs and encapsulate them in droplets, along with microbeads. Cell lysis within the droplet releases mRNAs and antibody-derived tags (ADT) for microbead capture before PCR amplification, size separation, and single cell RNA sequencing (scRNA-seq).
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Deanna earned their PhD from McGill University in 2020, studying the cellular biology of aging and cancer. In addition to a passion for telomere research, Deanna has a multidisciplinary academic background in biochemistry and a professional background in medical writing, specializing in instructional design and gamification for scientific knowledge translation. They first joined The Scientist's Creative Services team part time as an intern and then full time as an assistant science editor. Deanna is currently an associate science editor, applying their science communication enthusiasm and SEO skillset across a range of written and multimedia pieces, including supervising content creation and editing of The Scientist's Brush Up Summaries.
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Bacteria cooperate to benefit the collective, but cheaters can rig the system
When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.
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