Health authorities in both countries announced that people under certain age cutoffs are now ineligible for the Spikevax COVID-19 shot due to its association with heart inflammation.

If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.

Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.

Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.

The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.

Researchers find traces of SARS-CoV-2 in the stool and blood of kids with the post–COVID-19 inflammatory disorder, and signs of increased intestinal permeability.

Some children who experience the severe inflammatory condition after COVID-19 may continue to experience milder problems such as muscle weakness or anxiety even after that period, according to a small observational study in the UK.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

Researchers have collected hundreds of COVID-19–related diabetes case reports since August of last year, in hopes of teasing apart the complex links between the two diseases.

Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.