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Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Immunity-Linked Genes Expressed Differently in Brains of Autistic People

Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.

Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.

inflammation
Illustration of HIV virus
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD | Dec 12, 2022 | 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 
Illustration showing immunology during pregnancy
Infographic: How Immunology Can Influence Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 3 min read
Pregnancy-induced changes in the immune system are key to a successful birth. Understanding those changes could allow researchers to protect both mother and child.
Human brain stock photo
New Insight into Brain Inflammation Inspires New Hope for Epilepsy Treatment 
Deanna MacNeil, PhD | 3 min read
Clinicians and researchers teamed up to investigate how inappropriate proinflammatory mechanisms contribute to the pathogenesis of drug-refractory epilepsy.
Illustration of pregnancy and the immune system
Modulating Immunity to Improve Pregnancy Outcomes
Tobias R. Kollmann, Arnaud Marchant, and Sing Sing Way | Nov 14, 2022 | 10+ min read
Aberrant immune activation, the main cause of prematurity and stillbirths, could be preventable through interventions such as maternal vaccination. 
an immune cell in blood
Why Viral Infections Are More Severe in People with Down Syndrome
Andy Carstens | Oct 14, 2022 | 6 min read
In people with the genetic condition, inflammation can cause a mild infection to snowball out of control, a study finds.
A man working at a computer late at night
Shift Work Early in Life Results in Increased Stroke Severity in Middle Age
Jennifer Zieba, PhD | 3 min read
Researchers found that shifted sleep/wake cycles in young rats result in increased functional deficits and mortality following stroke later in life.
News feature
Vector image of black body with head surrounded by white clouds
Multiple Possible Causes of Long COVID Come into Focus
Natalia Mesa, PhD | Sep 28, 2022 | 10+ min read
Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.  
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez, PhD | Aug 5, 2022 | 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Discover the microbiome’s role in diabetes 
A Question of Balance: How the Gut Microbiome Influences Diabetes
The Scientist Creative Services Team | 1 min read
The presence of beneficial or detrimental microbes pulls the host toward health or disease.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
hands of a person checking their blood glucose level with a monitor
Growing Evidence Ties COVID-19 to Diabetes Risk
Bianca Nogrady | May 3, 2022 | 7 min read
Studies suggest SARS-CoV-2 infection could trigger the development of diabetes in some people, even those with no other risk factors.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist Creative Services Team | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
illustration of thymus in white on a green background
New Mechanism for Virus-Triggered Autoimmunity Uncovered
Sophie Fessl, PhD | Mar 11, 2022 | 4 min read
Roseolovirus infection disrupts how the body trains immune cells not to attack it, a mouse study shows.
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022 | 10+ min read
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
Small Changes, Big Consequences
Small Changes, Big Consequences
Niki Spahich, PhD | 3 min read
To understand the mechanisms behind severe COVID-19, researchers identified common COVID-19 genetic risk variants that affect immune cell function.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 2 min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Illustration of clear cells with orange nuclei, Toxoplasma gondii, on colorful background
Turning Toxoplasma Against Cancer
Annie Melchor | Jan 3, 2022 | 9 min read
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
red defocused lights
Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study
Rachael Moeller Gorman | Dec 10, 2021 | 4 min read
Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements.
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