Senior woman wearing a grey pullover, sitting on a bed, and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
ABOVE: © ISTOCK.COM, NICKYLLOYD
Early Inflammation Protects Against Chronic Pain, Study Finds
Early Inflammation Protects Against Chronic Pain, Study Finds

Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.

Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.

ABOVE: © ISTOCK.COM, NICKYLLOYD

inflammation

hands of a person checking their blood glucose level with a monitor
Growing Evidence Ties COVID-19 to Diabetes Risk
Bianca Nogrady | May 3, 2022
Studies suggest SARS-CoV-2 infection could trigger the development of diabetes in some people, even those with no other risk factors.
illustration of thymus in white on a green background
New Mechanism for Virus-Triggered Autoimmunity Uncovered
Sophie Fessl | Mar 11, 2022
Roseolovirus infection disrupts how the body trains immune cells not to attack it, a mouse study shows.
Cytokine storm
The Next Generation of Immunoassays Support COVID-19 Research
The Scientist Creative Services Team in collaboration with Bio-Techne | Dec 14, 2021
An automated, microfluidic immunoassay system enables researchers to quickly and reliably measure cytokines in patient blood samples.
Conceptual image showing fragmented X chromosomes
How Chaos in Chromosomes Helps Drive Cancer Spread
Samuel F. Bakhoum | Mar 1, 2022
A new link between inflammation and rampant chromosomal abnormalities reveals novel strategies to treat diverse malignancies.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
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Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis
The Scientist Creative Services Team in collaboration with Sartorius | Sep 8, 2021
Discover how to image and quantitate phagocytosis in real time
Illustration of clear cells with orange nuclei, Toxoplasma gondii, on colorful background
Turning Toxoplasma Against Cancer
Annie Melchor | Jan 3, 2022
Several research groups have found that Toxoplasma gondii infection can ramp up antitumor immune responses in mice. Can the single-cell parasite be used to develop safe treatments for humans?
red defocused lights
Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study
Rachael Moeller Gorman | Dec 10, 2021
Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements.
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Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model
Roni Dengler, PhD | Aug 16, 2021
Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine.
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
Central Nervous System Modeling with iPSC-Derived Cells
The Creative Services Team in collaboration with BrainXell | Jun 8, 2021
Bryan Black and Lucas Thal will discuss their experiences screening hiPSC-derived neural cells to understand chronic pain and neuroinflammation.
December 2021 - Gut Guests - Infographic
Infographic: How Worms that Reside in the Gut Could Influence Health
Catherine Offord | Dec 1, 2021
Research in animals and people supports a range of mechanisms by which the parasites affect physiology and immune responses.
A watercolor of a baby in a heart-shaped womb
Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy
Amanda Heidt | Oct 20, 2021
Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds.
Cancer Vaccines: Raising a T Cell Army
Niki Spahich, PhD | Apr 1, 2021
Vaccines against various forms of cancer prime the immune system to attack.
adolescent getting vaccination shot
Moderna Vaccine Paused for Young People in Two European Countries
Chloe Tenn | Oct 6, 2021
Health authorities in both countries announced that people under certain age cutoffs are now ineligible for the Spikevax COVID-19 shot due to its association with heart inflammation.
illustration of a coronavirus and antibodies
When the Immune Response Makes COVID-19 Worse
Alejandra Manjarrez | Sep 27, 2021
If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.
Understanding Immune-Mediated Damage After Respiratory Infection
The Scientist Creative Services Team in collaboration with 10x Genomics | Feb 17, 2021
Paul Thomas from St. Jude Children’s Research Hospital will discuss how he used single cell and spatial transcriptomics to discover the underlying mechanism of an inflammatory immune response in the lungs.
A multicolored section of a fruit fly brain
Tumors Disrupt the Blood-Brain Barrier at a Distance
Abby Olena | Sep 9, 2021
Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.