Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome
Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.
Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

inflammation
Breaking Down Barriers
Breaking Down Barriers
The Scientist Creative Services Team | Oct 19, 2020
Looking at the future of neurodegeneration research!
Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Shawna Williams | Sep 29, 2020
The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.
Steroid Drugs Are an Effective Treatment for Severe COVID-19: WHO
Steroid Drugs Are an Effective Treatment for Severe COVID-19: WHO
Catherine Offord | Sep 3, 2020
A meta-analysis of seven randomized controlled trials concludes that dexamethasone and other corticosteroids reduce 28-day mortality in seriously ill patients.
Could COVID-19 Trigger Chronic Disease in Some People?
Could COVID-19 Trigger Chronic Disease in Some People?
Katarina Zimmer | Jul 17, 2020
A handful of viruses have been associated with long-term, debilitating symptoms in a subset of those who become infected. Early signs hint that SARS-CoV-2 may do the same.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
Could Statins Reduce the Severity of COVID-19?
Could Statins Reduce the Severity of COVID-19?
Ashley Yeager | Jun 12, 2020
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.
Could Curbing Runaway Immune Responses Treat COVID-19?
Could Curbing Runaway Immune Responses Treat COVID-19?
Shawna Williams | Apr 21, 2020
Drugs targeting patients’ immune systems, rather than the virus itself, could be key to recovery from severe cases of the disease, some researchers suggest.
Discovered: Metabolic Mechanism of Cytokine Storms
Discovered: Metabolic Mechanism of Cytokine Storms
Ruth Williams | Apr 15, 2020
By studying influenza in mice and cells, researchers identify a glucose metabolism pathway critical to the dysregulated immune response that kills many infectious disease patients, including those with COVID-19.
Lost Smell and Taste Hint COVID-19 Can Target the Nervous System
Lost Smell and Taste Hint COVID-19 Can Target the Nervous System
Ashley Yeager | Mar 24, 2020
The symptoms suggest SARS-CoV-2 might infect neurons, raising questions about whether there could be effects on the brain that play a role in patients’ deaths, but the data are preliminary.