Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy
Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy
Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds.
Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy
Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy

Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds.

Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds.

inflammation
Moderna Vaccine Paused for Young People in Two European Countries
Moderna Vaccine Paused for Young People in Two European Countries
Chloe Tenn | Oct 6, 2021
Health authorities in both countries announced that people under certain age cutoffs are now ineligible for the Spikevax COVID-19 shot due to its association with heart inflammation.
When the Immune Response Makes COVID-19 Worse
When the Immune Response Makes COVID-19 Worse
Alejandra Manjarrez | Sep 27, 2021
If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.
Tumors Disrupt the Blood-Brain Barrier at a Distance
Tumors Disrupt the Blood-Brain Barrier at a Distance
Abby Olena | Sep 9, 2021
Shoring up the tissues that separate neurons and other brain cells from the circulatory system in fruit flies and mice can prolong life in the presence of a tumor.
Neuron-Released Protein Can Set Off Inflammation: Study
Neuron-Released Protein Can Set Off Inflammation: Study
Marcus A. Banks | Aug 19, 2021
Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions.
Bacterial Infections Disrupt Flies’ Sense of Smell
Bacterial Infections Disrupt Flies’ Sense of Smell
Abby Olena | Jul 21, 2021
The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick.
SARS-CoV-2 Antigens Leaking from Gut to Blood Might Trigger MIS-C
SARS-CoV-2 Antigens Leaking from Gut to Blood Might Trigger MIS-C
Alejandra Manjarrez | Jun 3, 2021
Researchers find traces of SARS-CoV-2 in the stool and blood of kids with the post–COVID-19 inflammatory disorder, and signs of increased intestinal permeability.
Severe Symptoms of MIS-C Typically Clear Within Six Months: Study
Severe Symptoms of MIS-C Typically Clear Within Six Months: Study
Catherine Offord | May 26, 2021
Some children who experience the severe inflammatory condition after COVID-19 may continue to experience milder problems such as muscle weakness or anxiety even after that period, according to a small observational study in the UK.
Spleen-to-Liver Signals Control Systemic Inflammation
Spleen-to-Liver Signals Control Systemic Inflammation
Ruth Williams | Apr 29, 2021
In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Rachael Moeller Gorman | Apr 1, 2021
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
A Global Registry Aims to See if COVID-19 Causes Diabetes
A Global Registry Aims to See if COVID-19 Causes Diabetes
Asher Jones | Mar 19, 2021
Researchers have collected hundreds of COVID-19–related diabetes case reports since August of last year, in hopes of teasing apart the complex links between the two diseases.
A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena | Jan 20, 2021
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome
Catherine Offord | Oct 6, 2020
Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.
Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Kids’ Severe COVID-19 Reaction Bears Unique Immune Signature
Shawna Williams | Sep 29, 2020
The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.