Induced neural progenitor cells (iNPCs), derived from induced pluripotent stem cells (iPSCs), are a relatively new method for modeling the cellular interactivity, biochemical alterations, and functional changes found in neurodegenerative and neuropsychological diseases. Key advances in iNPC culture and repatterning have made iNPCs an attractive way to study diseases for which no adequate laboratory model exists, but questions remain about the model’s applicability to in situ disease. To explore the pros and cons of using iNPCs as a model for neuronal function and dysfunction, The Scientist is bringing together a panel of experts to share their experience with iNPCs and their forecast for iNPC disease modelling for human disease. Attendees will have the opportunity to interact with the experts, ask questions, and seek advice on topics that are related to their research.
Topics to be covered:
- Using iNPCs to study neuronal dysfunction in neurological diseases
- Culture guidelines and modifications for...
Meet the Speakers:
Kristen Brennand, PhD
Departments of Psychiatry and Neuroscience
Icahn School of Medicine at Mount Sinai
Wenbin Deng, PhD
Department of Biochemistry and Molecular Medicine
UC Davis School of Medicine