Researchers linkurl:report; that they have overcome one of the major roadblocks to using small interfering RNA (siRNA) therapeutically - they have developed a new method to linkurl:deliver siRNA; to silence genes in specific cells in vivo, according to this week's Science. "I'm really actually quite excited about the paper," said linkurl:John Rossi,; who works on siRNA therapeutics and gene therapy at City of Hope in Duarte, California, and who was not involved in the research. "I really think this is a big breakthrough." In the same issue of the journal, two other groups of researchers linkurl:announce; that they have linkurl:developed; a technique using RNA interference to identify a new type of target for cancer therapeutics. Researchers have lauded the promise of siRNA as a tool for studying gene function as well as a potential therapeutic technique, but difficulties with delivering siRNA molecules into cells has dogged the field. linkurl:Motomu...
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