New Technology Spurs on Proteomics

Graphic: Leza BerardoneOne recent morning at the Applied Biosystems proteomics research center in Framingham, Mass., scientist Jason Marchese patiently used a pipettor to place tiny samples onto a 2-inch-by-2-inch plate. He was surrounded by technology as simple as 2-D gel electrophoresis apparatus and as cutting-edge as a high-throughput system that uses automated robotics for multidimensional liquid chromatography separation of proteins and an automated workstation that uses the latest in mass

Written byJennifer Fisher Wilson
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The only scientist working in a large room filled with machines for proteomics research, Marchese talked about how he can load protein sample onto machines in the afternoon and return the next day to a database full of newly identified proteins. But in spite of major advances like this, inadequate technology still holds back the field of proteomics. Applied Biosystems is just one of a number of biotechnology companies working hard to provide novel tools to identify more quickly and precisely the thousands upon thousands of proteins produced by the human body.

Now that the human genome is mapped, researchers in academia, government, and industry have turned their attention to mapping proteins. And biotechnology companies are responding by developing the needed tools for the job. Already a multimillion-dollar business, proteomics is expected to grow quickly into a multibillion-dollar business, according to market estimates.

"It was important to map the genome, ...

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