After Decades of Delays, RSV Vaccines Show Promise in Early Data

Both Pfizer and GSK have shared preliminary data suggesting that their experimental vaccines can protect older adults and newborn infants from the virus.

Written byDan Robitzski
| 3 min read
A vial labeled “RSV vaccine” on a reflective surface next to a syringe and stethoscope.
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Based on preliminary clinical trial data, two experimental vaccines for respiratory syncytial virus, a major cause of infant mortality around the world, seem to offer robust protection to the groups most at risk from the pathogen: newborn children and elderly adults. The dual announcements represent the most promising progress toward a vaccine for RSV to date, according to the Associated Press, following decades of roadblocks—and reluctance among pharmaceutical companies to tackle the problem after earlier clinical trials failed.

RSV is a seasonal virus that typically spreads in the fall and winter. It poses a mild, cold-like annoyance to most otherwise healthy adults, according to the AP, but each year it hospitalizes roughly 58,000 children under the age of five (several hundred of whom die from the disease) in the US, and it kills roughly 100,000 children around the world. The virus also hospitalizes approximately 177,000 and kills 14,000 adults over ...

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    Dan is an award-winning journalist based in Los Angeles who joined The Scientist as a reporter and editor in 2021. Ironically, Dan’s undergraduate degree and brief career in neuroscience inspired him to write about research rather than conduct it, culminating in him earning a master’s degree in science journalism from New York University in 2017. In 2018, an Undark feature Dan and colleagues began at NYU on a questionable drug approval decision at the FDA won first place in the student category of the Association of Health Care Journalists' Awards for Excellence in Health Care Journalism. Now, Dan writes and edits stories on all aspects of the life sciences for the online news desk, and he oversees the “The Literature” and “Modus Operandi” sections of the monthly TS Digest and quarterly print magazine. Read more of his work at danrobitzski.com.

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