Organ Engineer Re-Examined for Misconduct

The Karolinska Institute may reopen its investigation into the work of artificial trachea researcher Paolo Macchiarini based on stories presented in a Swedish documentary series.

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An artificial trachea, similar to those transplanted by Macchiarini, made by seeding an inorganic scaffold with stem cellsUCL Stories presented in a Swedish documentary series have prompted the Karolinska Institute to re-examine its investigation of Paolo Macchiarini, the regenerative medicine researcher and surgeon the institution cleared of misconduct in August 2015, Retraction Watch reported this week (February 1). Macchiarini previously faced allegations of misrepresenting data in papers leading to his implantation of artificial tracheae in patients.

“The programmes contained information that was unknown to the university management, which means that the inquiry into suspected scientific misconduct might be reopened against Professor Macchiarini,” the institute said in a January 28 statement. “My conclusion is that we need to examine and evaluate the claims made in the documentary, and will be reopening the inquiry if there is reason to do so,” added Karolinska Vice-Chancellor Anders Hamsten.

Among other things, the documentary series reported that Macchiarini performed surgical experiments on patients in Russia whose conditions, Retraction Watch noted, did not “warrant such a risky procedure.”

“If the information presented is true, the activities in Russia do not comply with KI rules and what we expect from our employees,” Karolinska spokesperson Claes Keisu told Nature.

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