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A seven-protein complex drives blood clotting by initiating actin polymerization in platelets.

Elevated levels of enzyme myelencephalon-specific protease in MS lesions could represent drug target.

Loci on chromosomes two, three and 20 are implicated in susceptibility to myocardial infarction.

and mammalian cells

Two independent research teams in Europe and the US have identified a defective gene that increases susceptibility to Crohn's disease.

Almost three-quarters of acute cardiac events in premenopausal women occur between days one and five of the menstrual cycle.

A vaccine that protects monkeys against Ebola virus has been developed but there's still some way to go before a human version is available.

Between the ages of six and eight months, babies' brains go through a crucial stage of development that allows them to begin to make sense of objects.

Experts fear that Eastern Europe could experience an AIDS epidemic similar to that seen in Africa.

An international trial has shown that intravascular radiotherapy can prevent artery re-narrowing after stent implantation.

A study in sheep shows that BSE can be transmitted between individuals of the same species by whole blood transfusion.

LONDON, 14 September (SPIS MedWire). Stem cell transplantation may offer hope to patients with advanced kidney cancer - usually considered an incurable illness. According to a report in today's New England Journal of Medicine, 19 patients with metastatic renal cell carcinoma, which had not responded to conventional therapy, received low-dose chemotherapy and immunosuppression followed by stem cell transplantation from a related donor. In seven patients there was shrinkage of metastases, and thre

Quality of care for acute MI patients is better in teaching hospitals, perhaps because they practice evidence-based medicine.

A new study provides evidence that the damaging effect of smoking is at least in part accounted for by an increased oxidative stress.

LONDON, September 11 (SPIS MedWire). Elevated levels of serum C-reactive protein (CRP) - indicative of systemic inflammation - are associated with a blunted systemic endothelial vasodilatation, report a team from Johann Wolfgang Goethe University in Frankfurt. Their findings, published in Circulation, add further credibility to the theory that the link between inflammation and cardiovascular risk is mediated by endothelial dysfunction. Fichtlschere et al measured forearm blood flow responses to