M.H. Polymeropoulos, C. Lavedan, E. Leroy, S.E. Ide, A. Dehejia, A. Dutra, B. Pike, H. Root, J. Rubenstein, R. Boyer, E.S. Stenroos, S. Chandrasekharappa, A. Athanassiadou, T. Papapetropoulos, W.G. Johnson, A.M. Lazzarini, R.C. Duvoisin, G. Di Iorio, L.I. Golbe, R.L. Nussbaum, "Mutation in the *-synuclein gene identified in families with Parkinson's disease," Science, 276:2045-7, June 27, 1997. (Cited in more than 250 papers since publication)

Comments by Robert L. Nussbaum, chief of Genetic Disease Research Branch, National Human Genome Research Institute

Robert L. Nussbaum
Sometimes it seems like research progress hits a wall. That was the case in the early '90s with Parkinson's disease, remembers Robert L. Nussbaum. "There was this general feeling that the basic, underlying cause still had not been discovered," Nussbaum notes. Parkinson's patients and their families got impatient. Then they got organized. Zack Hall, then the director of the National Institute of Neurological...

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