ProCipitate(tm)

LigoChem, a company based in Fairfield New Jersey, has introduced ProCipitate for the rapid and efficient isolation of nucleic acids. Based on patented Polymer Bridging Network technology, ProCipitate is one of a family of reagents with unique properties: Electropherosequence data of BAC DNA prepared by the TIGR ProCipitate Filterplate (TPF) method. Good quality DNA is consistently obtained with this method, which, using ABD BigDye Terminator sequencing chemistry -- yields high signal strength

| 2 min read

Save for Later

Listen with Speechify

0:00

2:00

Electropherosequence data of BAC DNA prepared by the TIGR ProCipitate Filterplate (TPF) method. Good quality DNA is consistently obtained with this method, which, using ABD BigDye Terminator sequencing chemistry -- yields high signal strengths, low backgrounds and long reads.

LigoChem's ProCipitate AI Work: Protein binds witin the polymer matrix of ProCipitate while the unreacted nucleic acid is rejected into the supernatant.

It is an anionic, supercharged polymer, which in its initial state is fully extended. The introduction of protein causes the formation of salt bridges and the liberation of water. As the charge on the polymer is neutralized, the network literally collapses on itself, recoiling like a spring.

ProCipitate can be purchased ...

Interested in reading more?

Become a Member of

Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!

Join for free today

Already a member?