Research Notes

The Jury is Still Out on Soy In the search for a breast cancer preventive, soy has been considered a promising candidate. But a review of research on soy's phytoestrogen genistein (K.B. Bouker, L. Hilakivi-Clarke, "Genistein: Does it prevent or promote breast cancer," Environmental Health Perspectives, 108:70-8, August 2000) is lukewarm on the compound's preventative capabilities. "There is no strong evidence that genistein would actually prevent breast cancer, but there is no strong evidence

Written byHarvey Black
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

In the search for a breast cancer preventive, soy has been considered a promising candidate. But a review of research on soy's phytoestrogen genistein (K.B. Bouker, L. Hilakivi-Clarke, "Genistein: Does it prevent or promote breast cancer," Environmental Health Perspectives, 108:70-8, August 2000) is lukewarm on the compound's preventative capabilities. "There is no strong evidence that genistein would actually prevent breast cancer, but there is no strong evidence that genistein would increase risk either," says Leena Hilakivi-Clarke, an associate professor of oncology at Georgetown University. Even though the evidence that genistein would increase breast cancer risk is not very persuasive, the authors do state that "studies indicating a potential breast cancer risk should not be taken lightly" and there is a "paramount" need to understand its potential to promote breast cancer. Genistein may play a role in promoting breast cancer, says Hilakivi-Clarke, when malignant cells are present in the breast. The ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research