ANDRZEJ KRAUZE
“What human trial would propose studying the effect of a drug only in 43-year-old males who are all twin brothers living in one small town in California, with identical studio apartments, identical educations, identical monotonous jobs, identical furniture, identical monotonous diets, identical locked thermostats set to uncomfortably cold temperatures, where the house is cleaned by a grizzly bear that erases all of their social media every two weeks?”
This challenge to fellow biomedical researchers, issued in the pages of the journal Lab Animal in April of this year (doi:10.1038/laban.1224), was accompanied by a proposal that was no less bold: solve science’s reproducibility crisis and problems with translating laboratory biology to humans by overhauling how animal research is conceived of and conducted. The five authors of ...