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Researchers Find a Eukaryotic mRNA Policing System

The Faculty of 1000 is a Web-based literature awareness tool published by BioMed Central. It provides a continuously updated insider's guide to the most important peer-reviewed papers within a range of research fields, based on the recommendations of a faculty of more than 1,400 leading researchers. Each issue, The Scientist publishes a review, like the one above, that examines related papers in a single field. We also publish a selection of comments on interesting recent papers from the Faculty

Written byMignon Fogarty
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Each issue, The Scientist publishes a review, like the one above, that examines related papers in a single field. We also publish a selection of comments on interesting recent papers from the Faculty of 1000's output. For more information visit www.facultyof1000.com.

But critical as mRNAs are, cells have reasons to destroy them. For example, cells sometimes make errors when producing mRNAs and they need ways to purge the aberrant messages. "The whole process, like many biological reactions, is a balance in terms of how fast you can do it, and how many mistakes you can make; just like a normal factory," explains Roy Parker, associate investigator, department of molecular and cellular biology and biochemistry and molecular biophysics, University of Arizona, and an author on two papers recently highlighted by F1000.1,2 "So, if you look at the whole process of making and using mRNAs, there are lots of ways the cell ...

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