genotype associated with most resistance are susceptible to BSE
Resistance to transmissible spongiform encephalopathies (TSEs) in sheep can be influenced by polymorphisms of the gene that encodes prion protein (
Houston et al. inoculated infected cattle-brain homogenate into the brain of sheep with different PrP genotypes and investigated their resistance to transmission of BSE. They observed that VRQ and ARQ sheep developed the disease, and that 3 out of 19 ARR/ARR sheep showed clinical symptoms of BSE. In ...
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