Admittedly, I am a biased observer on this issue. Colorado was one of the few states with the foresight to invest some of its proceeds (from the national Master Settlement Agreement with the tobacco industry) in research focused on tobacco use and its consequences. Modeled after the highly successful research program in California, which is supported by a tax on tobacco products,2 the Colorado Tobacco Research Program (CTRP) funds a broad portfolio of projects ranging from molecular biology to policy analysis. Coordinated by the California program, CTRP applications undergo a rigorous peer review modeled after that of the National Institutes of Health. While this ensures that scientific excellence is maintained, the fact remains that our programs are mandated to support only research that is relevant to our mission—programs such as ours are indeed "targeted."
Ideally, a comprehensive funding agency should balance its support for both basic and applied sciences, since ...