Silence of the Lambs

A die-off of newborn lambs in Australia leads to the discovery of a new toxin and clues to a devastating liver disease in children.

Written byKerry Grens
| 4 min read

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IN TWO SHAKES: Two Australian lambs, one healthy, (right) and one with the biliary atresia-like syndrome (left)STEVE WHITTAKER

In 1988, Peter Windsor, then a veterinary pathologist for the New South Wales Department of Agriculture in Australia, received a call from a field veterinarian about several hundred newborn lambs that had died on a farm in a hilly region of the state near the Burrinjuck Dam. All of the lambs had been producing white feces and died within a few weeks of being born. Windsor asked to examine some of the animals, and upon post-mortem analysis of at least a dozen, “we found they didn’t have any gall bladders and their livers were already starting to develop early signs of cirrhosis,” he says. “This was new to me.”

But the pattern wasn’t entirely new to Australian farmers. In 1964, livestock had suffered a similar ...

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  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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