Sitting Pretty in Tough Times

Sitting pretty in tough times Infinity Pharmaceuticals — #1 (Small) By Tia Ghose Courtesy of Infinity Pharma Infinity Pharmaceuticals, an 8-year-old pharmaceutical company in Cambridge, Mass., jumped from fifth place in 2008 to the top spot on our list of best small companies. With an anticancer drug that targets the heat shock promoter 90 (HSP90) in several Phase II clinical trials, and a seven-month-old marriage to Purdue Pharmaceuti

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By Tia Ghose

Infinity Pharmaceuticals, an 8-year-old pharmaceutical company in Cambridge, Mass., jumped from fifth place in 2008 to the top spot on our list of best small companies. With an anticancer drug that targets the heat shock promoter 90 (HSP90) in several Phase II clinical trials, and a seven-month-old marriage to Purdue Pharmaceuticals, Infinity is flush with cash—and optimism—when most of the biotech sector is beset by financial woes.

The strategic alliance with Purdue, which involves joint commercialization of new drug targets, provided a fresh infusion of funds. Because of that, "we're expanding right now, in every single department," says Christian Fritz, senior director of the cancer biology group, who has been with Infinity since 2001. The 170-employee company is planning to hire over 30 people in 2009.

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