Sloppy Research Extracts A Greater Toll Than Misconduct

There has been much ado about fraud in science, and even more misunderstanding about its eventual importance in the efficient conduct of science, and our ability to police it. A report on a survey by Judith Swayze was headlined in the New York Times "... the myth that fraud in science is a rarity" (L.K. Altman, Nov. 23, 1993, page C3). In fact, as the text of the story took pains to emphasize, the study found that a majority of interviewees had heard of an example--in other words, that some fra

Written byJoshua Lederberg
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

The promulgation of fraud is an outrage, striking at the moral roots of the scientific enterprise. But its moral stridency is large, I submit, compared to its practical importance in most scientific fields. A much larger toll is exacted from inadequate experimental design and sloppy execution. The lost effort that is expended in straightening out muddy claims, or merely in plowing through their presentation in the literature, greatly exceeds what can be attributed to intentional fraud.

We do not rely entirely on the intrinsic virtue of the scientific personality. We are all human, and not equally socialized into the deepest respect for the truth, nor equally well trained to avoid even simple logical and statistical fallacies. It is the scientific system of organized skepticism, to borrow Robert K. Merton's phrase, that maintains the integrity of the enterprise.

Scientific claims enter into a cognitive network of great complexity. Rarely is work ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina

Products

nuclera logo

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo