Special Report: Cell Biologists Combine Old And New Tools

In 1663, English physicist Robert Hooke viewed cork under a microscope and observed that "these pores, or cells, were not very deep, but consisted of a great many little boxes." Although Hooke's discovery, which involved only the outer boundaries of cells, is considered the beginning of cell biology, it was nearly 200 years before two Germans, botanist Matthias Jakob Schleiden and physiologist Theodor Schwann, focused attention on the microcosm of life in the cell. Hooke, Schleiden, Schwann, a

| 10 min read

Register for free to listen to this article
Listen with Speechify
0:00
10:00
Share

Hooke, Schleiden, Schwann, and the many others who painted the early portraits of cells would be astounded if they could see the state of cell biology today. Researchers now order cells from catalogs, charging them to grant numbers or credit cards. Cancer cells and blood cells are routinely fused to create a totally new cell type, the hybridoma. Thanks to genetic engineering, tobacco cells glow with a firefly's light, mice manufacture human antibodies, corn plants produce bacterial insecticide, and bacteria churn out human pharmaceuticals. In California, a man sues his doctor to recoup profits from cell lines derived from his cancerous spleen; throughout the world, laboratories abound with HeLa cells, descended from the cancerous cervix of a woman named Henrietta Lacks, who died in 1953, quite unaware that her cells would live on.

Optics Carl Zeiss Inc. One Zeiss Dr. Thornwood, N.Y. 10594 Phone: (914) 747-1800 Product: DynaCELL workstation: Contact ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Ricki Lewis

    This person does not yet have a bio.

Published In

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Faster Fluid Measurements for Formulation Development

Meet Honeybun and Breeze Through Viscometry in Formulation Development

Unchained Labs
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital

Products

Metrion Biosciences Logo

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Biotium Logo

Biotium Unveils New Assay Kit with Exceptional RNase Detection Sensitivity

Atelerix

Atelerix signs exclusive agreement with MineBio to establish distribution channel for non-cryogenic cell preservation solutions in China

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo