Success with Stem Cell Neurons

Light-controlled neurons made from human embryonic stem cells can activate neural circuits in mice.

Written byRuth Williams
| 3 min read

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WIKIMEDIA COMMONS, NICOLAS P. ROUGIER

Neurons made from human embryonic stem cells (hESCs) can both send and receive nerve impulses when transplanted into the mouse brain, according to a report published today (November 21) in Proceedings of the National Academy of Sciences. The discovery provides some of the strongest evidence that hESC-derived neurons, which could be used to treat a variety of neurological disorders such as epilepsy, stroke, and Parkinson’s disease, can fully integrate and behave like regular neurons when transplanted into the brain.

“We’ve known for decades that [transplanted neurons] can receive information,” said Jason Weick of the University of Wisconsin, who was the lead author on the study. Once the cells are in the brain, he explained, their electrical activity can be simply recorded. The missing part of ...

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Meet the Author

  • ruth williams

    Ruth is a freelance journalist. Before freelancing, Ruth was a news editor for the Journal of Cell Biology in New York and an assistant editor for Nature Reviews Neuroscience in London. Prior to that, she was a bona fide pipette-wielding, test tube–shaking, lab coat–shirking research scientist. She has a PhD in genetics from King’s College London, and was a postdoc in stem cell biology at Imperial College London. Today she lives and writes in Connecticut.

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