Swimming in a Smaller Pond

Julie Olson goes from cutting deals at Pfizer to adjusting her Big Pharma attitude for life at a startup.

Written byKeith O'Brien
| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

Julie Olson has seen the future, and it is in polymers. A former Pfizer executive, Olson is the CEO of Mersana Therapeutics, a 12-person startup in Cambridge, Mass., that is developing a biodegradable, bio­inert polymer called Fleximer, which when linked to certain anticancer agents may make the drugs more soluble, less toxic to the body, and more effective in attacking tumors. In short, Fleximer, if successful, could take a drug that has failed due to high levels of toxicity and help it succeed today.

Olson fell in love with the idea in 2004, joined the company (then named Nanopharma) as its CEO, and began a crash course in how to run a small startup. It hasn't always been easy, but with Phase I testing on Mersana's first compound approaching in early 2007, Olson's colleagues say her 18 years at Big Pharma gave her at least some of the tools to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies