Scientists studying pathogens such as Chlamydia, Legionella, and Listeria get a master class in how to control the internal workings of mammalian cells.
In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.
The dissection of how cells sense and propagate physical forces is leading to exciting new tools and discoveries in mechanobiology and mechanomedicine.