Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

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antibody-dependent enhancement

Zika Infection Increases Risk of Severe Dengue Fever
Ruth Williams | Aug 27, 2020
A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.
For the Greater Good: A Profile of Eva Harris
Diana Kwon | Jul 13, 2020
Through groundbreaking studies on dengue and efforts to build scientific infrastructure in Latin America, the University of California, Berkeley, professor has bridged research with its benefits to society.
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COVID-19 Vaccine Researchers Mindful of Immune Enhancement
Katarina Zimmer | May 26, 2020
There is no evidence that any of the coronavirus vaccines in development worsen a coronavirus infection rather than confer immunity to it, but the phenomenon is something scientists are closely monitoring.
Dengue Infection Impairs Immune Defense Against Zika
Catherine Offord | Aug 18, 2017
A memory B cell response to Zika virus in dengue-infected patients produced antibodies that were poorly neutralizing in vitro and instead enhanced infection.