Directly activating a heat sensor also sensitive to capsaicin in chili peppers in the hypothalamus had the same effect as exercise.

A protein secreted by osteoblasts crosses the blood-brain barrier to regulate hunger in mice.

The tendency of Labrador retrievers to overeat is tied to their genes, researchers report.

A hormone made in the liver controls how much sugar mice eat, according to a study.

A second patient taking an experimental medication to treat Prader-Willi Syndrome has died of blood clots.

A single nucleotide polymorphism in BDNF is tied with lower levels of the protein and higher body-mass index.

Weight-loss drugs that target newly characterized obesity-related receptors and pathways could finally offer truly effective fat control.

Cannabinoids cause appetite-suppressing neurons to produce an appetite-stimulating hormone in mice.