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David Hogness, Revolutionary of 20th Century Genetics, Dies
The Stanford University researcher’s groundbreaking work connected the fields of molecular biology and genetics, paving the way for the founding of genomics.
David Hogness, Revolutionary of 20th Century Genetics, Dies
David Hogness, Revolutionary of 20th Century Genetics, Dies

The Stanford University researcher’s groundbreaking work connected the fields of molecular biology and genetics, paving the way for the founding of genomics.

The Stanford University researcher’s groundbreaking work connected the fields of molecular biology and genetics, paving the way for the founding of genomics.

chromosomes
Unbalanced Chromosomal Inheritance More Common than Thought
Jef Akst | Oct 11, 2019
A genomic analysis from 23andMe suggests that people inherit two copies of a chromosome from only one parent nearly twice as often as researchers had realized.
nettie stevens x and y chromosome name origin the scientist
How Chromosomes X and Y Got Their Names, 1891
Joseph Keierleber | Mar 1, 2019
A quirk of nomenclature originates in the study of insect cells.
Filling in the Gaps: Sequencing the Entire Human Genome
The Scientist Speaks - Filling in the Gaps: Sequencing the Entire Human Genome
Iris Kulbatski, PhD
Karen Miga discusses how she and collaborators sequenced the missing parts of the human genome almost two decades after the first Human Genome Project published its results.
Condensin Folds DNA Through Loop Extrusion
Diana Kwon | Jun 1, 2018
By observing the activity of a protein complex in real time, researchers have uncovered new evidence for a long-standing theory.
Rare Disease Geneticist: A Profile of Uta Francke
Anna Azvolinsky | May 1, 2018
The Stanford University human geneticist identified the genes and genomic abnormalities underlying numerous rare diseases, including Rett  syndrome, and advanced the field of molecular diagnostics. 
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018
Errors in segregation during cell division can lead to inflammation in daughter cells.
Another Bird Telomere Study, Different Results
Anna Azvolinsky | Mar 21, 2018
Two studies examining the effects of parents’ ages on their offsprings’ telomere lengths come to opposite conclusions.  
Birds With Older Fathers Have Shorter Telomeres, Lifespans
Anna Azvolinsky | Mar 14, 2018
The findings contradict what has been observed in humans.  
Image of the Day: DNA Knitter
The Scientist Staff and The Scientist Staff | Feb 27, 2018
Researchers show how condensin complexes organize DNA in real time.
A Brush with Inheritance, 1878
Catherine Offord | Feb 1, 2018
Lampbrush chromosomes, first observed in the 19th century, still offer an unparalleled glimpse into how genetic information is organized in the cell.
Captivated by Chromosomes
Anna Azvolinsky | Dec 1, 2017
Peering through a microscope since age 14, Joseph Gall, now 89, still sees wonder at the other end.
Dogs’ Friendly Demeanor Written in Their DNA
Bob Grant | Jul 20, 2017
Researchers pinpoint the genes that make pooches so dang affable.
Image of the Day: Colorful Chromosomes
The Scientist Staff | Mar 16, 2017
This 3-D model of the mouse genome depicts the interactions between chromosomes within an embryonic stem cell.
Five More Synthetic Yeast Chromosomes Completed
Anna Azvolinsky | Mar 9, 2017
Members of the Synthetic Yeast Genome Project have synthesized five additional yeast chromosomes from scratch. 
Early-Life Stress Affects Telomeres Later
Anna Azvolinsky | Oct 3, 2016
An accumulation of stressful events in childhood is associated with shorter telomeres as a person ages, researchers report. 
Aneuploid Responses
Catherine Offord | May 1, 2016
A recent exchange of papers is divided over the evidence for compensatory gene expression among wild strains of aneuploid yeast.
A Scrambled Mess
Karen Schindler | May 1, 2016
Why do so many human eggs have the wrong number of chromosomes?
Meiotic Mysteries
Karen Schindler | Apr 30, 2016
Understanding why so many human oocytes contain the wrong number of chromosomes