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COVID-19 Infections May Reshape Genetic Landscape
COVID-19 Infections May Reshape Genetic Landscape
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests.
SARS-CoV-2 infection triggers structural changes in the host cell’s DNA, which provide a molecular explanation for long COVID, a new study suggests.
cohesin
Mutated Cohesin Throws DNA Splicing out of Whack, Resulting in Cancer
Shafaq Zia | Mar 3, 2023 | 2 min read
Cohesin mutations cause dysregulations in alternative splicing, contributing to tumor initiation and progression, a study finds.
Mechanism of a Genome Packaging Machine Discovered
Ruth Williams | Jan 17, 2022 | 3 min read
Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.
Infographic: How Genome-Packaging Protein Cohesin Handles DNA
Ruth Williams | Jan 17, 2022 | 1 min read
The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.