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Image of a road cutting through a field under a blue sky with clouds. On the road, the years “2025”, “2026”, “2027”, “2028” are painted leading down the road. 2026 is in orange. This represents the outlook for research in 2026.
| 7 min read
US researchers saw many challenges in 2025. With a new NIH budget, some are optimistic for the year ahead, while others remain skeptical as numerous obstacles remain.

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The David J. Sencer Museum at the headquarters of the Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia

CDC Restructuring Aims to Improve Timeliness and Accountability

NIH Director Francis Collins receiving his first dose of the Moderna COVID-19 vaccine on December 2020.

Francis Collins to Retire as NIH Director by Year’s End

Donald Lindberg

Donald Lindberg, Former NLM Director, Dies

Former NIH Director James Wyngaarden Dies

AIDS Researcher Emerges as Top Candidate to Head CDC

Astrophysicist Nominated to NSF Helm

Interim NSF Director Announced

The Scientist Placeholder Image

First Female NIH Director Dies

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A person on an operation table getting anesthesia. A study revealed sex differences in ketamine anesthesia.

Female Brains Wake Up from Anesthesia Differently Than Male Brains

A woman in her 60s wears a yellow tank top and brown-rimmed glasses while placing a hormone-replacement patch on her upper arm.

Flawed Studies Linked Menopausal Hormone Therapy to Breast Cancer

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A hand holding $100 bills reaches out of a green-colored laptop screen, indicating a bribe.

Publisher Investigates an Alleged Peer Review Extortion Attempt

Multimedia

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
A model of a brain made of flat, multicolored pieces stacked together.

Mapping Tissues with Spatial Biology

August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

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Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi

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A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

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Conceptual image of ice and frost.

The VAULT100 PRO: Inside the most advanced Stirling Ultracold ULT freezer ever built.

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