Lucemyra is the first non-opioid drug to be approved in the U.S. specifically for this purpose.

Sex-deprived males seek out alcohol.

Scientists are beginning to unravel the mechanisms behind the therapeutic effects of psychedelic drugs.

A newly discovered painkiller does not cause respiratory depression or addiction in mice and could be an alternative to frequently abused prescription medicines, researchers report.

A modified bacterial protein elicits a robust immune response against a cocaine-linked molecule in mice.

Long-term marijuana smokers have less gray matter in their orbitofrontal cortex than nonsmokers, but other brain circuits may compensate by increasing connectivity.

Developing nonaddictive drugs to combat pain

Is it possible to make a nonaddictive opioid painkiller?

Augmenting the action of a glutamate receptor in the brains of addicted rats helps prevent them from seeking cocaine during withdrawal, a study shows.

At the Society for Neuroscience conference, researchers present results linking the epigenome to heroin and cocaine addiction.