Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
Cocaine Use Creates Feedback Loop with Gut Bacteria: Mouse Study
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
A jolt of norepinephrine in the mouse gut facilitates colonization by certain microbes, which in turn deplete glycine, enhancing cocaine-induced behaviors.
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
Some rats showed a decrease in addictive tendencies when researchers activated the pathway, while the behavior of others became more addictive when the pathway was inhibited.
A study in mice suggests serotonin release underlies the drug’s prosocial effects while dopamine mediates the rewarding properties that drive its potential for abuse.
Kamran Khodakhah, a researcher at the Albert Einstein College of Medicine, explains the cerebellum's newly described role in addictive and social behaviors.
A newly discovered painkiller does not cause respiratory depression or addiction in mice and could be an alternative to frequently abused prescription medicines, researchers report.
Long-term marijuana smokers have less gray matter in their orbitofrontal cortex than nonsmokers, but other brain circuits may compensate by increasing connectivity.