In his book’s Introduction, physician-scientist Paul A. Offit reviews the unusual constellation of circumstances around the development of COVID-19 vaccines.

President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.

The FDA granted the drug, called Aduhelm, accelerated approval earlier this summer in a process that’s since drawn scrutiny.

The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia.

The US Food and Drug Administration has called for a federal investigation of its own regulatory review process after widespread criticism of its decision on Aduhelm.

A lackluster performance in clinical trials of the monoclonal antibody aducanumab has left some experts unconvinced of its benefit.

Now more than ever before, recruiting patients for a research study doesn’t have to mean getting them to leave their homes.

Johnson & Johnson’s one-shot immunization could reach people’s arms as early as March 2.

As COVID-19 therapies get emergency-use green lights, the Biden administration must organize a therapeutic review board to help identify what’s working and what’s not.

Two new medications for treating a rare and deadly neuromuscular disease have high prices and questionable efficacies, say scientists.

Although scientists debate the ethics of deliberately infecting volunteers with SARS-CoV-2, plenty of consenting participants have been exposed to all sorts of pathogens in prior trials.

Researchers say the popularity of convalescent plasma makes it more difficult to gather high-quality data on its efficacy.

Screens of hundreds of drug excipients reveal that some can interact with biological targets, contradicting their FDA categorization as inert.

Vaccine experts divided on whether that level of protection is too low or too demanding.

Hydroxychloroquine and chloroquine, once thought to be promising COVID-19 treatments, come with serious heart risks.

Kennedy, who succumbed to COVID-19, served as commissioner of the FDA and editor-in-chief of Science, and is credited with helping to transform Stanford into a top research university.

Abbott’s ID NOW test missed the most positive samples among five products given the green light by the FDA to use during the pandemic.

Assembling the first COVID-19 test kits in the same room as coronavirus material, along with other practices that didn’t follow protocol, made the tests unusable, officials say.