Human Reference Genome Doesn’t Capture Full Genetic Diversity
Human Reference Genome Doesn’t Capture Full Genetic Diversity
A new analysis of 1,000 Swedes uncovers a chromosome’s worth of novel DNA sequences—much of them ancient—underscoring the need for a more diverse reference genome.
Human Reference Genome Doesn’t Capture Full Genetic Diversity
Human Reference Genome Doesn’t Capture Full Genetic Diversity

A new analysis of 1,000 Swedes uncovers a chromosome’s worth of novel DNA sequences—much of them ancient—underscoring the need for a more diverse reference genome.

A new analysis of 1,000 Swedes uncovers a chromosome’s worth of novel DNA sequences—much of them ancient—underscoring the need for a more diverse reference genome.

Human Genome Project
Opinion: Greater Diversity Is Needed in Human Genomic Data
Opinion: Greater Diversity Is Needed in Human Genomic Data
Charles Lee | Sep 1, 2019
Researchers must ensure that the inequality seen in most of today’s genomic studies and databases is corrected.
John Sulston, Human Genome Project Leader, Dies
John Sulston, Human Genome Project Leader, Dies
Kerry Grens | Mar 12, 2018
The biologist earned a Nobel Prize in 2002 for his work on C. elegans.
“Human Genome Project-Write” Unveiled
“Human Genome Project-Write” Unveiled
Jef Akst | Jun 2, 2016
A proposal to synthesize entire genomes—the subject of a controversial, invitation-only meeting at Harvard last month—is formally presented in Science.
Secret Genome Meeting
Secret Genome Meeting
Jef Akst | May 16, 2016
A closed-door gathering at Harvard last week hosted researchers talking about synthesizing entire genomes, including that of humans. 
Life After Sequencing
Life After Sequencing
Eva Amsen | Feb 1, 2016
Fifteen years after publication of the human genome’s first draft sequence, what has become of the hundreds of researchers who worked on the project?
Illuminating the Interactome
Illuminating the Interactome
Molly Sharlach | Nov 20, 2014
A massive screen yields the most comprehensive map of binary human protein interactions to date.
Human Gene Set Shrinks Again
Human Gene Set Shrinks Again
Jyoti Madhusoodanan | Jul 8, 2014
Proteomic data suggest the human genome may encode fewer than 20,000 genes.
Genome Digest
Genome Digest
Jyoti Madhusoodanan | Jul 1, 2014
What researchers are learning as they sequence, map, and decode species’ genomes
Sharing the Wealth
Sharing the Wealth
Jef Akst | May 1, 2014
From research results to electronic health records, biomedical data are becoming increasingly accessible. How can scientists best capitalize on the information deluge?