liver

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally.

Brain cells in older Drosophila tend to have more than two complete sets of chromosomes, and that polyploidy most likely has a protective function, a study shows.

Scientists uncover a potential reason why redder house finches have better health.

Researchers find strains of the bacterium Klebsiella pneumoniae that produce high levels of alcohol in 60 percent of patients with the condition.

A small study finds that the tiny extracellular vesicles from patients with hepatocellular carcinoma have RNA content distinct from patients with cirrhosis only.

In mice, seeing and smelling food causes immediate cellular changes that ready the liver to convert incoming amino acids to proteins.

Separate proof-of-concept studies report success against two inherited diseases.

Even in mice with a busted circadian clock and an unhealthy diet, carefully timed feeding overcomes the rodents’ predispositions for metabolic diseases.

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.

Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop. 

Mounting evidence suggests that intermittent fasting causes significant changes to various organs and tissue types.

Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.