Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

The 44-year-old patient has Hunter syndrome, which doctors hope to treat using zinc finger nucleases.

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

Tissue “seeds” made up of three cell types and patterned onto a scaffold develop into complex structures with some organ function, researchers show.

Using human induced pluripotent stem cells, scientists grew liver organoids and studied gene expression patterns in individual cells to learn more about how these tissues develop. 

Mounting evidence suggests that intermittent fasting causes significant changes to various organs and tissue types.

Sangamo Therapeutics will use zinc finger nucleases to introduce the gene for a missing clotting factor into the livers of men with hemophilia B.