Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.
Immunotherapy Treats Fibrosis in Mice
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Immunotherapy Treats Fibrosis in Mice
Immunotherapy Treats Fibrosis in Mice

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

liver disease
Ribbon diagram of the protein coat of an adeno-associated virus
Preprints Propose Constellation of Causes for Kids’ Liver Disease
Christie Wilcox | Jul 25, 2022
Two independent groups suggest the suite of recent unexplained hepatitis cases may stem from coinfection with an adeno-associated virus and a helper adeno- or herpesvirus, a duo which may be especially virulent in children with a particular genetic variant.
Liver glowing red underneath human torso
Mysterious Hepatitis Cases Reported in Young Children
Natalia Mesa | Apr 18, 2022
Officials have ruled out known hepatitis viruses as the cause of a rash of illnesses in Europe and the US.
LabTalk Podcast - The Promise of Spatial Transcriptomics in Exploring Chronic Liver Disease
The Scientist Creative Services Team and 10x Genomics | Jun 30, 2021
Prakash Ramachandran discusses using spatial transcriptomics to understand liver fibrosis and what he can learn from analyzing biobanked tissue samples.
Rotonya Carr, University of Pennsylvania, Perelman School of Medicine, underrepresented minority researchers, funding, academic medical centers, COVID-19, pandemic, SARS-CoV-2
Q&A: Unique Circumstances for Minority Scientists During COVID-19
Asher Jones | Mar 10, 2021
Investigators from underrepresented groups have borne the brunt of the disruption to science from the pandemic, according to an opinion piece that outlines ways in which institutions can lessen the damage.
Organoids Repair Bile Ducts
Abby Olena | Feb 18, 2021
Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally.
a photo of glasses of beer
Alcohol-Related Deaths in US Doubled in Past Two Decades: Study
Emily Makowski | Jan 8, 2020
White women had the highest increase in death rate.
Gut Microbe Linked to Nonalcoholic Fatty Liver Disease
Abby Olena | Sep 19, 2019
Researchers find strains of the bacterium Klebsiella pneumoniae that produce high levels of alcohol in 60 percent of patients with the condition.
CRISPR Editing Heads Off Disease in Mouse Livers
Shawna Williams | Oct 9, 2018
Separate proof-of-concept studies report success against two inherited diseases.
Allergan’s Buying Spree Rolls On
Bob Grant | Sep 21, 2016
The Ireland-based pharma company makes a $1.7 billion offer to acquire Tobira Therapeutics, a US firm developing liver disease drugs.
Improving Gene Therapy with In Vivo Selection
Tanya Lewis | Jun 8, 2016
Scientists have developed a way to selectively expand genetically modified hepatocytes in mice.
Triglyceride Clock
Abby Olena | Feb 10, 2014
The timing of meals affects the levels of lipids in the livers of mice, according to a study.
Obesity-Cancer Link Detailed
Chris Palmer | Jun 26, 2013
Obesity drives an alteration of the gut microbiome, leading to the secretion of metabolites associated with the development of liver cancer.
Synthetic Spirits
David Nutt | Jan 1, 2011
Can we use science to reduce the harms of alcohol?