lncRNA

Although epigenetic changes were long thought to largely act on the genome, rather than as part of it, research is now showing that these patterns can, directly or indirectly, change the genetic code.

Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.

Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.

Using a modified CRISPR approach, scientists shed light on the diversity and function of 499 long noncoding RNAs.

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa

Epigenetic changes accrued over an organism’s lifetime may leave a permanent heritable mark on the genome, through the help of long noncoding RNAs.

Genes that react to cellular sugar content are regulated by a long non-coding RNA via an unexpected mechanism

Long, non-coding regions of RNA can prevent red blood cells from committing suicide during the final stage of differentiation.