The gel, which men rub on their upper bodies daily, delivers synthetic progestin to block the testes from producing normal levels of sperm.

Researchers injected a non-hormonal hydrogel contraceptive into 16 male rhesus monkeys, finding that it prevented pregnancy for an entire breeding season.

Two drugs targeting a protein in sperm cause reversible infertility in male mice, providing new hope for a male contraceptive.

In a proof-of-principle study, genetic deletion of two genes renders male mice infertile by preventing sperm transport through the vas deferens.

A small molecule that inhibits a protein important for chromatin organization can cause reversible sterility in male mice.

New research suggests that controlling cytoskeletal dynamics in sperm accessory cells may help regulate male fertility.