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Oocytes and Obesity
Ashley P. Taylor | Feb 10, 2015
Eggs from excessively overweight mothers suffer mitochondrial damage that can be averted with pharmacological intervention, a mouse study finds.
Gut Microbes Trigger Malaria-Fighting Antibodies
Molly Sharlach | Dec 4, 2014
A carbohydrate antigen found on cells of
and other species prompts a potent immune response against malaria-causing parasites in mice.
Lab Versus House Mouse
Jef Akst | Aug 21, 2014
Some behavioral traits, like female aggression, were lost with domestication, a study shows.
Epigenetic Changes Can Cause Cancer
Ashley P. Taylor | Jul 25, 2014
A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model.
Fixing Protein Folding
Abby Olena | Dec 9, 2013
A small molecule that stabilizes a misfolded receptor can treat symptoms of a genetic mutation in mice, researchers show.
Do Mice Make Bad Models?
Dan Cossins | Feb 11, 2013
A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.
Dan Cossins | Nov 13, 2012
What researchers are learning as they sequence, map, and decode species’ genomes
Lab Rats Need Better Diets
Hayley Dunning | Jul 18, 2012
Rodents fed all-you-can-eat diets may be skewing experimental results.
Fasting Heightens Chemotherapy Benefits
Hannah Waters | Feb 8, 2012
Starvation paired with cancer drugs slowed or stopped unchecked cell growth in yeast and mouse models of cancer, outpacing or matching the isolated effects of chemo.