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Gut Microbes Need Fiber, Too
Karen Zusi | Jan 13, 2016
A low-fiber diet decimated the diversity of bacterial species in mice colonized with human gut microbes in a recent study.
Rina Shaikh-Lesko | Aug 13, 2015
Researchers find evidence to suggest why an enzyme crucial for fighting off malaria infection is linked to a form of lymphoma.
The Dark Side of Melanin
Anna Azvolinsky | Feb 19, 2015
Researchers uncover a previously unknown way UV light can act on melanin, spurring cancer-causing mutations hours after sun exposure.
Oocytes and Obesity
Ashley P. Taylor | Feb 10, 2015
Eggs from excessively overweight mothers suffer mitochondrial damage that can be averted with pharmacological intervention, a mouse study finds.
Gut Microbes Trigger Malaria-Fighting Antibodies
Molly Sharlach | Dec 4, 2014
A carbohydrate antigen found on cells of
and other species prompts a potent immune response against malaria-causing parasites in mice.
Lab Versus House Mouse
Jef Akst | Aug 21, 2014
Some behavioral traits, like female aggression, were lost with domestication, a study shows.
Epigenetic Changes Can Cause Cancer
Ashley P. Taylor | Jul 25, 2014
A transgene designed to attract methylation to the promoter of a tumor-suppressor gene leads to tumorigenesis in a mouse model.
Fixing Protein Folding
Abby Olena | Dec 9, 2013
A small molecule that stabilizes a misfolded receptor can treat symptoms of a genetic mutation in mice, researchers show.
Do Mice Make Bad Models?
Dan Cossins | Feb 11, 2013
A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.
Dan Cossins | Nov 13, 2012
What researchers are learning as they sequence, map, and decode species’ genomes