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Abstract, colorful illustration of the human brain.
A Gene Therapy to Treat the FOXG1 Brain Disorder 
By postnatally providing a transcription factor important for brain development, researchers fixed abnormalities generated in utero in mice.
A Gene Therapy to Treat the FOXG1 Brain Disorder 
A Gene Therapy to Treat the FOXG1 Brain Disorder 

By postnatally providing a transcription factor important for brain development, researchers fixed abnormalities generated in utero in mice.

By postnatally providing a transcription factor important for brain development, researchers fixed abnormalities generated in utero in mice.

mouse model

Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution
Viewing the Glioblastoma Tumor Microenvironment at Single Cell Resolution
The Scientist Staff | Apr 9, 2024 | 1 min read
In this webinar, Matthias Brendel will discuss a new PET approach called scRadiotracing, which involves immunomagnetic cell sorting after in vivo radiotracer injection combined with 3D histology.
Albert Quintana wears a lab coat and stands against a background of laboratory equipment.
The Culprits Behind Motion Sickness
Hannah Thomasy, PhD | Feb 1, 2024 | 2 min read
Scientists identified neurons that drive the disagreeable symptoms of motion sickness in mice.
A microRNA Family Drives the T Cell Response in Cancer
Niki Spahich, PhD | Nov 11, 2023 | 4 min read
When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation.
Image of cochlear implant and hearing aid.
Reversing Hearing Loss
Laura Tran, PhD | Nov 1, 2023 | 2 min read
Gene reactivation restored hearing after loss in mice, but the timing of intervention is key.
A clinician holding a graphic of the lungs on a tablet
Stem Cells Breathe New Life into Lungs
Aparna Nathan, PhD | Oct 30, 2023 | 3 min read
New studies proposed using stem cells to make long-lasting lung grafts.
Kaitlyn Sadtler standing in front of a laboratory bench
Spectral Flow Cytometry: Separating the Fluorophore Rainbow
Charlene Lancaster, PhD | Oct 24, 2023 | 3 min read
Spectral flow cytometry separates similarly emitting fluorophores and enabled Kaitlyn Sadtler to construct a 24-color rat panel for immunological analyses.
A graphic of the female reproductive system
Differentiated Stem Cells Can Kickstart Fertility in Mice
Aparna Nathan, PhD | Oct 23, 2023 | 3 min read
Ovarian cells derived from stem cells restore hormones and cells needed to produce pups.
Artistic rendering of a cancer cell in red with round, blue accents
Targeting Breast Cancer Metastasis
Tanvir Khan, PhD | Oct 16, 2023 | 3 min read
Researchers inhibited molecules that regulate both tumor and immune cell migration and their crosstalk signaling to impede metastasis.
<em >The Scientist</em>&rsquo;s Journal Club: Olfaction and the Brain
The Scientist’s Journal Club: Olfaction and the Brain
The Scientist | Oct 5, 2023 | 1 min read
Gonzalo Otazu will discuss how the brain processes smells differently in neurotypical mice compared to a mouse model of autism spectrum disorder.
A repeating pattern of cartoon mice on an orange background.
An Introduction to Humanized Immune System Mouse Models
Taconic | Sep 15, 2023 | 1 min read
Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. 
Close up on eyes of mother and daughter faces next to one another
A Long and Unhealthy Life?
Aparna Nathan, PhD | Sep 13, 2023 | 3 min read
A new mouse model shows that the Myc protein has complex effects on aging and cancer.
Understanding Hybridoma Technology for Monoclonal Antibody Production
Understanding Hybridoma Technology for Monoclonal Antibody Production
Alpana Mohta, MD | May 9, 2023 | 5 min read
By fusing antibody-producing cells with immortal myeloma cells, researchers produce reliable supplies of highly specific antibodies.
Bladder epithelial tissue, where cell junctions are shown in green and nuclei in blue. This was grown in vitro from cells taken from mice with chronic cystitis.
Bladder ‘Memory’ Influences Urinary Tract Infection Recurrence in Mice
Alejandra Manjarrez, PhD | Apr 12, 2023 | 3 min read
Urinary tract infections leave permanent epigenetic marks in the mouse bladder epithelium, reprogramming its response to subsequent infections, a study finds.
Surface rendering of microscopy image showing two dendritic cells (green) communicating with a nociceptor neuron (violet).
How Cells in the Skin Team Up To Fight Pathogens
Rachael Moeller Gorman | Apr 12, 2023 | 4 min read
Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.
Histological stain of in blue, red, and green of tumor
Self-Charging Battery Battles Tumors in Mice
Natalia Mesa, PhD | Apr 4, 2023 | 3 min read
A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.
Photograph of scientists working while wearing PPE
Contract Vivarium Facilities for Preclinical Discovery
The Scientist and Mispro | Mar 30, 2023 | 3 min read
Researchers rent contract vivarium space for greater experimental control, productivity, and reproducibility when developing new therapeutics.
Structure of a Chlamydomonas, green algae
Drugs Hitch a Ride on Algae for Targeted Delivery
Holly Barker, PhD | Feb 1, 2023 | 3 min read
A new microrobot uses algae to transport antibiotics into the lungs of mice with pneumonia.
Illustration showing microscopic algae swim through mouse lungs and deliver nanoparticles of an antibiotic attached to their surfaces
Infographic: Algae Robots Transport Antibiotics to Infected Tissues
Holly Barker, PhD | Feb 1, 2023 | 1 min read
Microscopic algae dotted with drug-filled nanoparticles may offer a more effective means of treatment than traditional delivery methods.
Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Dan Robitzski | Jan 25, 2023 | 6 min read
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
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