Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.
Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

mouse model
Image of the Day: Gastric Colonies
Image of the Day: Gastric Colonies
Chia-Yi Hou | May 6, 2019
Scientists map the presence of Helicobacter pylori in the stomach of mice, showing where the bacteria colonize the gastric glands.
Image of the Day: Cone Preservation
Image of the Day: Cone Preservation
Chia-Yi Hou | Apr 30, 2019
Researchers treat mice with retinitis pigmentosa using a gene therapy that reduces cone loss.
Image of the Day: Powerful Protein
Image of the Day: Powerful Protein
Chia-Yi Hou | Apr 25, 2019
An experiment tests whether a protein treatment can help hematopoietic stem cells recover after mice are exposed to radiation.
Image of the Day: Colorful Colonoids
Image of the Day: Colorful Colonoids
Chia-Yi Hou | Apr 18, 2019
Organoids grown from a mouse’s colon will be used to screen drugs for colorectal cancer.
Microbes May Take Some of the Blame for the Reproducibility Crisis
Microbes May Take Some of the Blame for the Reproducibility Crisis
Emma Yasinski | Apr 5, 2019
Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.
Image of the Day: Tuft Cells
Image of the Day: Tuft Cells
Chia-Yi Hou | Apr 3, 2019
After a severe case of flu, mice have chemosensory cells in their lungs, a place where they don’t normally occur.
Rapidly Flashing Lights and Sounds Reduces Alzheimer’s in Mice
Rapidly Flashing Lights and Sounds Reduces Alzheimer’s in Mice
Jef Akst | Mar 15, 2019
Exposing mice to an hour of 40-hertz stimuli every day for a week reduced levels of amyloid-β plaques and tau protein, and improved cognition.
CAR T Cells Treat Lupus in Mice
CAR T Cells Treat Lupus in Mice
Abby Olena | Mar 6, 2019
T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.
Four Sets of Mice Call Popular Autism Theory into Question
Four Sets of Mice Call Popular Autism Theory into Question
Sarah DeWeerdt | Feb 26, 2019
Signaling imbalance, driven by too much excitatory activity, may be a consequence of whatever brain changes lead to autism rather than a cause of the condition.